What is Selank?
Selank (TP-7) is a heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a synthetic analogue of tuftsin, an endogenous tetrapeptide involved in immune modulation. Selank is notable for being one of the few nootropic peptides with published controlled clinical research.
⚠ Research Purposes Only: Selank is a research chemical not approved by the FDA (USA) or MHRA (UK) for human consumption. All information is for educational purposes only.
Published Research on Selank
The most significant published research on Selank comes from Russian clinical trials. A study by Semenova et al. (2010) examined Selank's anxiolytic effects in patients with generalised anxiety disorder and neurasthenia, finding significant reductions in anxiety scores compared to placebo and a comparator drug (medazepam).
| Study Focus | Finding | Research Context |
|---|---|---|
| Anxiety (GAD) | Significant reduction in HAMA scores | Controlled clinical trial |
| Memory/Cognition | Improved attention and working memory | Animal & preliminary human data |
| Immune Modulation | IL-6 upregulation observed | Preclinical models |
| Tolerability | Well-tolerated in studies | Clinical research |
Selank Mechanism of Action
Selank appears to modulate the expression of brain-derived neurotrophic factor (BDNF) and serotonin metabolism, while also influencing enkephalin degradation — which may explain the anxiolytic effects. Unlike benzodiazepines, it does not bind to GABA-A receptors, which researchers note as a distinction in terms of mechanism.
Selank vs Semax — Research Comparison
| Parameter | Selank | Semax |
|---|---|---|
| Primary Effect | Anxiolytic / anti-anxiety | Cognitive / nootropic |
| Mechanism | BDNF, serotonin modulation | BDNF, dopamine pathway |
| Administration | Nasal spray or injection | Nasal spray or injection |
| Clinical Data | Yes (Russian trials) | Yes (Russian trials) |
🔬 Where to Source Selank for Research (USA & UK)
For USA and UK researchers, RCD.bio is one of the most reliable sources with third-party certificates of analysis. All products are for research purposes only and not approved for human consumption.
Visit RCD.bio →⚠ Affiliate link — use code Tomjunkie for 20% off. Research purposes only.
Frequently Asked Questions
Selank is researched for its anxiolytic (anti-anxiety) and nootropic effects. Published Russian clinical trials show significant reductions in anxiety scores. It is a research chemical not approved for human consumption.
Selank research has used intranasal and injection administration routes. It is a peptide and is typically reconstituted from lyophilised powder for research use.
RCD.bio is a highly-rated vendor for Selank with third-party certificates of analysis available. For research purposes only.
No. Selank does not bind to GABA-A receptors like benzodiazepines. Its mechanism appears to involve BDNF modulation and serotonin metabolism — a distinct mechanism from classical anxiolytics.