What is RAD-150?
RAD-150 (TLB-150) is a SARM derived from RAD-140 through an esterification process. The addition of a benzoate ester group extends the compound's half-life, which research suggests results in more stable androgen receptor activation over time compared to unesterified RAD-140.
It is a newer research compound than RAD-140 and has less published human clinical data available. Most research is preclinical at this stage, making it a compound of interest primarily in laboratory settings. For research purposes only.
⚠ Research Purposes Only: RAD-150 is a research chemical with no approved human use. It is not approved by the FDA or MHRA for human consumption.
RAD-150 vs RAD-140 — Research Comparison
| Parameter | RAD-150 | RAD-140 |
|---|---|---|
| Chemical Form | Esterified (Benzoate) | Unesterified |
| Half-Life (est.) | 48+ hours | 15–20 hours |
| Human Trial Data | Limited (preclinical) | Phase I complete |
| Onset | Slower (ester cleavage) | Faster |
| Research Maturity | Early stage | Well-documented |
Why Researchers Are Interested in RAD-150
The primary research interest in RAD-150 over RAD-140 is the extended half-life created by the benzoate ester. In theory, this would allow less frequent administration in research protocols while maintaining consistent androgen receptor occupancy. However, this remains largely theoretical as published human data is very limited.
Preclinical models have shown similar anabolic selectivity to RAD-140, with the ester group being cleaved in vivo to release RAD-140 as the active compound.
Suppression Research
Like RAD-140, RAD-150 is expected to suppress the hypothalamic-pituitary-testicular axis. Given the longer half-life, suppression may persist for longer periods after discontinuation compared to RAD-140. Post-cycle research compounds like TUDCA are often studied alongside SARM protocols.
🔬 Where to Source RAD-150 for Research (USA & UK)
For USA and UK researchers, SwissChems is one of the most reliable sources with third-party certificates of analysis. All products are for research purposes only and not approved for human consumption.
Visit SwissChems →⚠ Affiliate link — use code Tomjunkie for 20% off. Research purposes only.
Frequently Asked Questions
RAD-150 is the esterified (benzoate) form of RAD-140, giving it a longer estimated half-life of 48+ hours versus 15–20 hours for RAD-140. Both are research chemicals not approved for human consumption.
RAD-150 has limited published human data compared to RAD-140, which has a completed Phase I trial. Most RAD-150 research is preclinical. For research purposes only.
SwissChems is a highly-rated vendor for RAD-150 with HPLC certificates of analysis available. For research purposes only.
Like RAD-140, RAD-150 is expected to cause HPTA suppression. Research protocols studying recovery often include post-cycle support compounds.